Crotalus durissus venom: biological effects and relevant applications

Autores

  • Lucelina Araújo Federal University of Ceara, Fortaleza, Ceara
  • Anna Conceição Federal University of Ceara, Fortaleza, Ceara
  • Duanny Cunha Federal University of Ceara, Fortaleza, Ceara
  • Glayciane Morais Federal University of Ceara, Fortaleza, Ceara
  • João Silveira Federal University of Ceara, Fortaleza, Ceara
  • Francisco Júnior Federal University of Ceara, Fortaleza, Ceara
  • Karen Macambira Federal University of Ceara, Fortaleza, Ceara
  • Steffi Araújo Federal University of Ceara, Fortaleza, Ceara
  • Nathalie Pessoa Federal University of Ceara, Fortaleza, Ceara
  • Janaina Evangelista Federal University of Ceara, Fortaleza, Ceara

Palavras-chave:

Snake Toxins, Crotoxin, Phospholipase A2, Gyroxin.

Resumo

Snakes have an important biological role in the ecological chain, as well as in scientific researches performed with the venoms produced by them, since the enzyme-protein fractions these substances possess have been studied as pharmacological tools for the discovery of new therapies. Snakes of the genus Crotalus have gained significant relevance in the scientific field, since the venom produced by these reptiles has been the target of researchers in a few decades, due to the composition and the effects that these substances can produce. In Brazil, a single species represents the genus, which is Crotalus durissus. This review demonstrates that even with the advancement in scientific research on the composition, role and application of the venom produced by the subspecies of Crotalus durissus snake, it is necessary to further study their fractions and their action potential, which also demonstrates the how rich are these active components in different fields of biomedicine.

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Publicado

2016-03-30

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