Association between polypharmacy and the adherence to pharmacological treatment in patients with diabetes

Kiarelle Lourenço Penaforte, Samila Torquato Araújo, Virginia Oliveira Fernandes, Islene Victor Barbosa, Virna Ribeiro Feitosa Cestari, Renan Magalhães Montenegro Júnior

Abstract


Objective: to evaluate the occurrence of polypharmacy and its association with the adherence to the pharmacological treatment in patients with diabetes mellitus type 2. Methods: cross-sectional study conducted with 235 patients with diabetes mellitus type 2 through interview about the demographic and clinical data, drug therapy prescribed and adherence to treatment. To analyze the data, we used Student t-tests and Chi-square, with significance level p<0.05. Results: polypharmacy was evidenced in 88.4% of cases with a predominance of moderate level. An average of 7.5 pills per person among the 19 types of prescribed drugs were used. Adherence to prescribed therapy was reported by 88.2% of patients evaluated and there was no association with polypharmacy (p=0.266). Conclusion: it was verified that polypharmacy is a condition of high prevalence and is not associated with worse adherence to therapy.

Keywords


Diabetes Mellitus, Type 2; Therapeutics; Polypharmacy; Medication Adherence; Nursing.

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DOI: http://dx.doi.org/10.15253/rev%20rene.v18i5.30829

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