Quality of life and muscle trophism of chronic kidney patients undergoing intradialytic exercise

Abstract

Introduction: Chronic Kidney Disease is characterized by the gradual and irreversible deterioration of renal function, impairing the removal of metabolic waste. Hemodialysis emerges as an essential renal replacement therapy, filtering the blood to eliminate harmful substances (sodium, potassium, chlorides) and excess fluids. However, despite its importance, hemodialysis can lead to adverse consequences: sarcopenia, catabolism, reduced protein synthesis, decreased physical fitness and quality of life. Objective: To analyze the impact of muscle training on the quality of life and muscle strength of individuals with chronic kidney disease undergoing continuous intradialytic cycle ergometry. Methods: This is a longitudinal, prospective, randomized, and blinded cohort study conducted through a continuous exercise protocol with a cycle ergometer during hemodialysis. Forty patients were selected and divided into 2 groups (G1 continuous group and G2 control group) for 4 weeks. Results: The difference between G2 and G1 was 72.21, with a confidence interval of -12.59 to 157.00; the difference between the groups was 1098.91, with a confidence interval of 789.25 to 1408.57 and an adjusted p-value of 0.0000000 in the context of quality of life. The Pimáx showed a difference of -123.20 (CI = -149.79 to -96.61) for G1 with an adjusted p-value of 0.0000000 and the evaluation of the triceps surae, in the contracted phase, the difference was 2.50 (CI = -0.61 to 5.60, p = 0.14). Conclusions: Exercise significantly improves the quality of life and functionality of patients with chronic kidney disease.