Effect of oral antihypertensive drugs on biochemical dosages in the elderly
DOI:
https://doi.org/10.15253/2175-6783.2016000600018Keywords:
Aged, Antihypertensive Agents, Drug-Related Side Effects and Adverse Reactions.Abstract
Objective: to compare serum levels of uric acid, glucose, potassium and sodium in elderly users and non-users of oral antihypertensive drugs. Methods: observational, case-control study, including 232 elderly people with mean age 68.9 ± 7.4 years, of which 116 use and 116 do not use oral antihypertensive drugs, of both genders, non-diabetic and with no renal disease. After venous blood collection, glucose and uric acid were measured by colorimetric method; and sodium and potassium by the ion-selective electrode method. Results: there was an association between use of antihypertensive drugs and elevations in serum uric acid levels (p=0.040). And, among the classes, diuretic drugs demonstrated in this study relation with changes in uric acid levels (p=0.02) when compared to the other classes. Conclusion: the use of antihypertensive drugs, especially diuretics, has been associated with an increase in serum uric acid levels in hypertensive users of oral antihypertensive drugs.Downloads
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Published
2016-12-21
How to Cite
Carvalho, M. E. M. de M., Alves, E. L. M., & Martins, M. do C. de C. e. (2016). Effect of oral antihypertensive drugs on biochemical dosages in the elderly. Rev Rene, 17(6), 858–865. https://doi.org/10.15253/2175-6783.2016000600018
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Research Article