Characteristics of patients with sepsis and/or septic shock admitted to an adult intensive care unit
DOI:
https://doi.org/10.36517/2175-6783.202526994993Keywords:
Sepsis; Intensive Care Units; Nursing; Epidemiology.Abstract
Objective: to analyze the epidemiological and clinical characteristics of patients diagnosed with sepsis and/or septic shock admitted to an intensive care unit. Methods: this was a retrospective observational study with documentary data collection, carried out by accessing the medical records of patients diagnosed with sepsis and/or septic shock in an intensive care unit. Data were collected using a semi-structured form, followed by descriptive and bivariate analyses and Poisson regression. Results: 188 medical records were analyzed, 77 (41%) of patients diagnosed with sepsis and 111 (59%) with septic shock, the majority (n=99; 52.7%) with a respiratory focus. The majority were male (n=106; 56.4%), with an average age of 57.9 years. Mean arterial pressure <65mmHg and creatinine >2mg/dl were significantly associated with death. Conclusion: sepsis and septic shock were more prevalent in males of advanced age who had comorbidities and behavioral risks. Death was more common in patients with hypotension and elevated creatinine. Contributions to practice: this study reinforces the importance of identifying patients at risk of sepsis and/or septic shock early. Identifying associated factors can help prioritize care and formulate targeted clinical protocols, optimizing the management of these conditions.
Downloads
References
1. Instituto Latino-Americano de Sepse (ILAS). Relatório de atividades: Ano de referência 2022 [Internet]. 2023 [cited Jan 6, 2025]. Available from: https://ilas.org.br/wp-content/uploads/2023/07/Relatorio-atividades-ILAS-2022.pdf
2. Silva IKM, Silva TA, Lira VRS, Nunes EAT, Barbosa KTF, Xavier AT, et al. Cuidados intensivos de enfermagem ao paciente com sepse: uma revisão integrativa. Enferm Bras. 2024;23(1):1453-62. doi: https://dx.doi.org/10.62827/eb.v23i1.gt21
3. Caetano PDT, Nascimento NJ, Pereira R. Indice de sepse em uti no Brasil e a importância da educação permanente com os profissionais de enfermagem e comunidade sobre sinais e sintomas de sepse. Rev Bras Reabil Ativ Física [Internet]. 2024 [cited Jan 7, 2025];12(2):69-75. Available from: https://estacio.periodicoscientificos.com.br/index.php/rbraf/article/view/2630/2157
4. Tosi RR, Boneto YGR, Santos PS, Moreira CN. Clinical-epidemiological profile of patients admitted with sepsis in an intensive care unit. Rev Contemp. 2024;4(6):e4853. doi: https://dx.doi.org/10.56083/RCV4N6-189
5. Almeida NRC, Pontes GF, Jacob FL, Deprá JVS, Porto JPP, Lima FR, et al. Analysis of trends in sepsis mortality in Brazil and by regions from 2010 to 2019. Rev Saúde Pública. 2022;56:25. doi: https://doi.org/10.11606/s1518-8787.2022056003789
6. Williams CYK, Edimburgo T, Elbers PWG, Thoral PJ, Ercole A. Application of the Sepsis-3 criteria to describe sepsis epidemiology in the Amsterdam UMCdb intensive care dataset. PLoS One. 2024:19(6):e0304133. doi: https://dx.doi.org/10.1371/journal.pone.0304133
7. Macedo PRB, Andrade VSM, Silveira SJS. Análise do perfil epidemiológico da sepse no Tocantins entre 2013-2023. Facit Business Technol J. 2024;53(1):259-76. doi: http://doi.org/10.5281/zenodo.13611044
8. Rüddel DT, Fröhlich H, Schwarzkopf D, Bloos F, Riessen R. Sepsis and underlying comorbidities in intensive care unit patients: analysis of the cause of death by different clinicians-a pilot study. Med Klin Intensivmed Notfmed. 2024;119(2):123-8. doi: http://doi.org/10.1007/s00063-023-01037-4
9. Gobbi LT, Rocha CK, Maciel LT, Costa CP. Epidemiological profile of hospitalizations due to Septicemia: Considerations in anesthetic practice. Braz J Implantol Health Sci. 2024;6(7):2747-60. doi: https://dx.doi.org/10.36557/2674-8169.2024v6n7p2747-2760
10. Dalmolin BL, Martins MFS, Comin MF, Tereza DM, Tessmann M. Profile of patients treated in an intensive care unit of a hospital in Southern Santa Catarina: a comparative analysis of the three years since implementation. Rev Adm Saúde [Internet]. 2023 [cited Jan 10, 2025];23(93):e362. Available from: http://cqh.org.br/ojs-2.4.8/index.php/ras/article/view/362
11. Bittencourt CM, Busanello J, Mocellin LP, Escobal APL, Garcia RP, Pinto DM. Prevalence and factors associated with the sepsis continuum in an adult intensive care unit. Rev Enf Contemp. 2024;13:e5743. doi: https://dx.doi.org/10.17267/2317-3378rec.2024.e5743
12. Santos JV, Araújo MRLL, Toledo MCM, Bomfim LC, Lessa AEC, Santos PRAR, et al. Epidemiological analysis and trends in sepsis mortality in Brazil from 2018 to 2022. Braz J Implantol Health Sci. 2024;6(8):5148-61. doi: https://doi.org/10.36557/2674-8169.2024v6n8p5148-5161
13. Gondim DGM, Teixeira BL, Mourão CML, Sousa IC. Conhecimento do enfermeiro em protocolo sepse na unidade de terapia intensiva. Rev Facul Paulo Picanço. 2024;4(2):1-14. doi: https://doi.org/10.59483/rfpp.v4n2111
14. Oliveira ESW, Tavares KVST, Reis RB, Pampolim G, Simões GMS. Clinical, sociodemographic profile and outcome of patients admitted to the intensive care unit of a philanthropic hospital in Vitória file of patients admitted to intensive care units. Clin Biopsy. 2023;1(2):124-32. doi: https://doi.org/10.54727/cbps.v1i2.21
15. Rudd KE, Johnson SC, Agesa KM, Shackelford KA, Tsoi D, Kievlan DR, et al. Global, regional, and national sepsis incidence and mortality, 1990–2017: analysis for the Global Burden of Disease Study. Lancet. 2020;395(10219):200-11. doi: https://doi.org/10.1016/S0140-6736(19)32989-7
16. Freire GHE, Machado Filho UM, Machado MOGP, Araujo AK, Martins CFB, Martinez VS, et al. Perfil epidemiológico e tendências temporais das internações por sepse no Brasil: um estudo de 2019 a 2023. Braz J Implantol Health Sci. 2024;6(3):1809-19. doi: https://dx.doi.org/10.36557/2674-8169.2024v6n3p1809-1819
17. Evans L, Rhodes A, Alhazzani W, Massimo A, Craig MC, Craig F, et al. Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021. Crit Care Med. 2021;49:e1063–e1143. doi: http://doi.org/10.1007/s00134-021-06506-y
18. Costa BI, Amorim ME, Guimarães MAR, Teles GAM, Silva LG. Care for critical patients with sepsis. Rev Ibero-Am Hum Ciênc Educ. 2023;9(6):1262-73. doi: https://doi.org/10.51891/rease.v9i6.10191
19. Mariano DR, Pereira JS, Garcia GF, Mascarenhas CB. Profile of patients with sepsis and septic shock in a trauma hospital: cross-sectional study. Enferm Foco. 2022;13:e-202255. doi: https://doi.org/10.21675/2357-707X.2022.v13.e-202255
20. Santos CL, Rufino RD. Atuação da enfermagem frente ao protocolo de sepse. RMS. 2024;6(2):170-8. doi: https://doi.org/10.37115/rms.v6i2.732
21. Luquetti CM, Balduino FS, Flores KS, Souza AB, Faria AOV, Vasconcelos Filho GM, et al. Manejo da sepse e choque séptico na emergência adulto: uma revisão protocolar. J Med Biosci Res. 2024;1(3):1038-49. doi: http://dx.doi.org/10.70164/jmbr.v1i3.186
22. Souza KFF, Melo CAV, Lima DB, Duarte GSN, Costa HKS, Silva MNN. Fatores de risco para sepse e o manejo dos enfermeiros da unidade de tratamento intensivo. Rev Recien. 2023;13(41):432-8. doi: https://dx.doi.org/10.24276/rrecien2023.13.41.432-438
23. Bertollo DP, Gomes ECZ, Ebrahim KC. Análise do perfil epidemiológico e mortalidade de pacientes que desenvolveram insuficiência renal aguda concomitante à sepse enquanto internados em unidade de terapia intensiva. Rev Ibero-Am Hum Ciênc Educ. 2024;9(12):867-75. doi: https://doi.org/10.51891/rease.v9i12.12812
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Rev Rene
This work is licensed under a Creative Commons Attribution 4.0 International License.
