Spatial distribution and autocorrelation of live births among mothers with advanced maternal age

Authors

DOI:

https://doi.org/10.36517/2175-6783.20262795914

Keywords:

Reproductive Behavior; Pregnancy; Advanced Maternal Age; Women’s Health; Spatial Analysis.

Abstract

Objective: to identify the spatial distribution and autocorrelation of live births among mothers with advanced maternal age. Methods: ecological study using data from the Live Birth Information System and population estimates. Births were analyzed considering advanced maternal age (≥35 years) in Brazil and its health regions from 2016 to 2023. Rates were calculated by quadrennium, and the spatial distribution was determined through natural breaks. Spatial autocorrelation was assessed using Moran’s indices to identify cluster patterns. Results: a total of 3,531,207 births from mothers aged 35 years or older were analyzed. The Northern region of Brazil presented the highest rates of births from pregnancies at advanced maternal age. The global Moran’s index was significant in all periods, confirming spatial autocorrelation. Conclusion: spatial analysis revealed territorial disparities, highlighting the usefulness of Moran’s index clusters for understanding the distribution of pregnancies at advanced maternal age. Contributions to practice: the findings guide reproductive planning, prenatal care, and the formulation of public policies addressing territorial inequalities related to pregnancies at advanced maternal age.

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Published

2026-02-24

Data Availability Statement

The authors declare that the data used in this study are publicly available within the Live Birth Information System. Processed data and generated maps can be requested from the corresponding author.

Issue

Section

Research Article

How to Cite

1.
Cargnin AVE, Piran CMG, Mori MM, Lehmkuhl CSF, Rodrigues YV dos S, Shibukawa BMC, et al. Spatial distribution and autocorrelation of live births among mothers with advanced maternal age. Rev Rene [Internet]. 2026 Feb. 24 [cited 2026 Feb. 25];27:e95914. Available from: https://periodicos.ufc.br/rene/article/view/95914