Cost of primary bloodstream infection and dimensions of impact: a scoping review

Authors

DOI:

https://doi.org/10.36517/2175-6783.20262796479

Keywords:

Patients; Catheter-Related Infections; Hospital Costs; Hospital Infection Control Program; Patient Safety.

Abstract

Objective: to map the costs and dimensions associated with the treatment of bloodstream infection in adult and pediatric patients. Methods: a scoping review conducted across five national and international databases and three gray literature databases. Results: of the 258 studies identified, 12 were included in the final sample. Costs associated with the treatment of bloodstream infections ranged from US$122.91 to US$439,015.00, with increased hospital stays ranging from 10 to 135 days. Qualitative analysis revealed increased morbidity and complications related to prolonged hospitalization, the need to implement interventions to mitigate risks, and the substantial financial burden imposed on healthcare systems. Conclusion: bloodstream infection constitutes an adverse event with significant clinical, economic, and organizational impact, as it is associated with prolonged hospitalization, increased morbidity and mortality, and greater demand for resources, thereby imposing a considerable burden on healthcare systems. Contributions to practice: the findings reinforce the importance of institutional policies focused on patient safety, as well as the adoption of preventive practices aimed at strengthening care outcomes and optimizing available resources.

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Published

2026-06-10

Data Availability Statement

The data and content supporting this study are contained within the manuscript itself.

Issue

Section

Review Article

How to Cite

1.
Silva JT, Khalaf DK, Roscoche KGC, Freire MH de S, Boller S, Costa Bueno B. Cost of primary bloodstream infection and dimensions of impact: a scoping review. Rev Rene [Internet]. 2026 Jun. 10 [cited 2026 Jun. 18];27:e96479. Available from: https://periodicos.ufc.br/rene/article/view/96479