Assessment of nursing students’ knowledge of blood transfusion and related factors

Authors

DOI:

https://doi.org/10.36517/2175-6783.20262796768

Keywords:

Blood Transfusion; Transfusion Reaction; Students, Nursing; Knowledge.

Abstract

Objective: to assess nursing students’ knowledge of blood transfusion and related factors. Methods: an observational, cross-sectional, analytical study conducted with 165 undergraduate nursing students. Students aged ≥18 years were included, and those with incomplete questionnaires were excluded. A structured instrument with adequate internal consistency was applied (Kuder–Richardson 20=0.84). The knowledge score was dichotomized as adequate (≥50% correct answers) and inadequate (<50%), according to the literature. Analysis was performed using Pearson’s Chi-square test, with estimation of odds ratio and 95% confidence intervals (p<0.05). Results: inadequate knowledge predominated (66.7%). Higher rates of correct answers were observed in protocol-based safety practices, whereas weaknesses were identified in critical steps such as patient identification, clinical monitoring, and venous access management. Adequate knowledge was associated with more advanced semesters and technical nursing training (p=0.040). Conclusion: students’ knowledge was predominantly inadequate, with gaps in critical steps of transfusion safety. Educational factors, such as academic progression and prior experience, positively influenced this knowledge. Contributions to practice: the findings highlight the need to restructure teaching on blood transfusion in undergraduate nursing education, incorporating active methodologies, clinical simulation, and training focused on critical steps of the transfusion process.

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References

1. Oliveira CCM, Jacinto AF, Neves HPB, Rodrigues ABFL, Lima Junior FA, Soares FMM. Analysis of the concept of transfusion reaction for nursing. Rev Enferm Atual In Derme. 2025;99(supl.1):e025072. doi: http://doi.org/10.31011/reaid-2025-v.99-n.supl.1-art.2569

2. Borges AR, Conceição BS, Andrade CHF, Oliveira LL, Queiroz LSS, Sampaio LFA, et al. Analysis of the concept of blood transfusion: implications for nursing care. Rev Enferm Atual In Derme. 2026;100(2):e026037. doi: https://dx.doi.org/10.31011/reaid-2026-v.100-n.2-art.2742

3. Tadasa E, Adissu W, Bekele M, Arega G, Gedefaw L. Incidence of acute transfusion reactions and associated factors among adult blood-transfused patients at Jimma University Medical Center, southwest Ethiopia: a cross-sectional study. Medicine. 2024;103(32):e39137. doi: https://dx.doi.org/10.1097/MD.0000000000039137

4. Farah RA, Mitri A, El Rahi H, Al Humaidan H, Rajab MH, Kemahli S. Knowledge of blood transfusion practices among medical students and residents. Asian J Transfus Sci. 2024;18(1):51-5. doi: https://doi.org/10.4103/ajts.ajts_150_21

5. Lee JJ, Tsang VWY, Chan MMK, O’Connor S, Lokmic-Tomkins Z, Ye F, et al. Virtual reality simulation-enhanced blood transfusion education for undergraduate nursing students: a randomised controlled trial. Nurse Educ Today. 2023;129:105903. doi: https://doi.org/10.1016/j.nedt.2023.105903

6. Akyol AD, Kankaya H, Özel F, Konakçı G. Blood transfusion knowledge and practice among nurses in Turkey: a scenario sample. Asian J Transfus Sci. 2025;19(1):79-84. doi: https://dx.doi.org/10.4103/0973-6247.375888

7. Abdullah D, Haris M, Ullah S, Ayaz K, Khan H. Assessing nurses knowledge and practices regarding safe blood transfusion in a tertiary care fospital of Peshawar. J Health Wellness Community Res. 2026;4(5):1-9. doi: https://dx.doi.org/10.61919/8nyvbs54

8. Gaur R, Mudgal SK, Suyal N, Sharma SK, Agarwal R, Raj R, et al. Nurses and nursing students’ knowledge regarding blood transfusion. J Integr Nurs. 2022;4(3):137-44. doi: https://doi.org/10.4103/jin.jin_39_22

9. Rodrigues ABFL, Dutra SVO, Santos MIT, Araujo LR, Ferreira ALH, Jacinto AF, et al. The effects of the clinical simulation of transfusion reactions on nursing students’ knowledge gain: a pragmatic clinical Trial. Educ Sci (Basel). 2025;15(6):693. doi: https://doi.org/10.3390/educsci15060693

10. Edea G, Tiki T, Oljira H, Megersa Y. Assessment of knowledge of blood transfusion and its associated factors among nurses and midwives at public hospitals in Ethiopia: cross-sectional study. Heliyon. 2024;10(18):e38090. doi: https://doi.org/10.1016/j.heliyon.2024.e38090

11. Soares FMM, Araujo LR, Rodrigues ABFL, Magalhães DS, Lima GK, Negri EC. Nursing care for adult patients undergoing blood transfusion: a scoping review. Aquichan. 2025;25(1):e2515. doi: https://doi.org/10.5294/aqui.2025.25.1.5

12. Oliveira DL, Souza TO, Medeiros TM. Characterization of nursing undergraduate students during the COVID-19: analysis of ethnic-racial and socioeconomic dimensions. Esc Anna Nery. 2024; 28:e20240029. doi: https://dx.doi.org/10.1590/2177-9465-ean-2024-0029en

13. Dallora AL, Andersson EK, Palm BG, Bohman D, Björling G, Marcinowicz L, et al. Nursing students’ attitudes toward technology: multicenter cross-sectional study. JMIR Med Educ. 2024;10:e50297. doi: https://doi.org/10.2196/50297

14. Simin D, Dolinaj V, Svitlica BB, Grujić J, Živković D, Milutinović D. Blood transfusion procedure: assessment of serbian intensive care nurses’ knowledge. Healthcare (Basel). 2024;12(7):720. doi: https://doi.org/10.3390/healthcare12070720

15. Mattia D, Schneider DG, Gelbcke FL, Ferreira MMF, Paladini EP, Santos JLG, et al. Construction and validation of indicators for nursing management in blood transfusion. Rev Bras Enferm. 2025;78(3):e20240229. doi: https://doi.org/10.1590/0034-7167-2024-0229

16. Ortiz JLC, Griffin I, Kazakova S V., Stewart PB, Kracalik I, Basavaraju SV. Transfusion‐related errors and associated adverse reactions and blood product wastage as reported to the National Healthcare Safety Network Hemovigilance Module, 2014–2022. Transfusion. 2024;64(4):627-37. doi: https://doi.org/10.1111/trf.17775

17. Brown C, Brown M. Blood and blood products transfusion errors: what can we do to improve patient safety? Br J Nurs. 2023;32(7):326-32. doi: https://doi.org/10.12968/bjon.2023.32.7.326

18. Dhiman Y, Raturi M, Kala M, Kusum A. Significance of mandating a dedicated hemovigilance nurse and objectification of ‘imputability’ levels. Experience from a hospital-based blood centre in India. Transfus Clin Biol. 2023;30(1):96-102. doi: https://doi.org/10.1016/j.tracli.2022.09.066

19. Apelseth TO, Kristoffersen EK, Strandenes G, Hervig T. Training of medical students in the use of emergency whole blood collection and transfusion in the framework of a civilian walking blood. Transfusion. 2023;63(S3):60-6. doi: https://doi.org/10.1111/trf.17343

20. Soares FMM, Dutra SVO, Lima GK, Rodrigues ABFL, Magalhães DS, Negri EC, et al. Development and content validation of a nursing clinical simulation scenario on transfusion reaction management. Int J Environ Res Public Health. 2024;21(8):1042. doi: https://doi.org/10.3390/ijerph21081042

21. Yoon H. Effects of immersive virtual reality blood transfusion nursing simulation on the skill performance, confidence and satisfaction of senior nursing students. Nurse Educ Pract. 2025;84:104337. doi: https://doi.org/10.1016/j.nepr.2025.104337

22. Papkiadeh SR, Taheri-Ezbarami Z, Taklimi MM, Leili EK, Razaghpoor A. Comparing the effects of problem- and task-based learning on knowledge and clinical decision-making of nursing students concerning the use of transfusion medicine in pediatric nursing: an educational quasi-experimental study in Iran. Heliyon. 2024;10(14):e34521. doi: http://doi.org/10.1016/j.heliyon.2024.e34521

23. Jayawardena CK, Groenier M, Nawarathna LS. Relationship of adaptive expertise of health professions educators with age, experience, academic rank, and their work performance during an altered academic environment. BMC Med Educ. 2024;24(1):862. doi: https://doi.org/10.1186/s12909-024-05838-9

24. Uzun B, Yılmaz V, Göklü S, Şahbaz U, Güvel H. Blood transfusion knowledge levels of nurses in İzmir Atatürk training and research hospital, Turkey. Transfus Clin Biol. 2024;31(2):62-9. doi: https://doi.org/10.1016/j.tracli.2024.01.001

25. Simsek AK, Alpar SE, Cayli N. Nurses’ self-efficiency levels in safe blood and blood component transfusion: the case of Turkey. Transfus Apher Sci. 2024;63(3):103888. doi: https://dx.doi.org/10.1016/j.transci.2024.103888

26. Dülger G, Okuroglu GK. Development of Safe Blood Transfusion Self‐Efficacy Scale for nurses: validity and reliability study. Transfus Apher Sci. 2024; 63(5):103984. doi: https://dx.doi.org/10.1016/j.transci.2024.103984

27. Conselho Federal de Enfermagem. Resolução Cofen no 709, de 19 de agosto de 2022 [Internet]. 2022 [cited Apr 12, 2026]. Available from: https://www.cofen.gov.br/resolucao-cofen-no-709-2022/

28. Hamed SAH, Ibrahim AIM, Ali ZAM, Abdelghani AAA, Ahmed RA, Taha STI, et al. Clinical audit of transfusion safety and monitoring at Al-Kareemat Specialized Complex, Sudan: a two-cycle quality improvement study. Cureus. 2026;18(2):e102769. doi: https://doi.org/10.7759/cureus.102769

Published

2026-07-09

Data Availability Statement

The authors state that all datasets are available in the body of the article.

Issue

Section

Research Article

How to Cite

1.
Oliveira J de S, Sousa KAV de, Conceição BS da, Borges AR, Rodrigues ABFL, Santos MIT dos, et al. Assessment of nursing students’ knowledge of blood transfusion and related factors. Rev Rene [Internet]. 2026 Jul. 9 [cited 2026 Aug. 3];27:e96768. Available from: https://periodicos.ufc.br/rene/article/view/96768