Vaccine hesitancy in families of children during the COVID-19 pandemic




Parents; Family; Child; Vaccination Refusal; COVID-19.


Objective: to identify the reasons that led families of children to vaccine hesitancy during the COVID-19 pandemic. Methods: qualitative study with semi-structured interviews carried out with 20 children's relatives, all of which were mothers of hospitalized children. Data was submitted to lexicographical analysis in the software Interface de R pour les Analyses Multidimensionnelles de Textes et de Questionnaires, using descending hierarchical classification. Results: the fear of leaving one’s house during the pandemic and the lack of vaccine supplies were the reasons found for vaccine hesitancy in the family of children during the COVID-19 pandemic. Conclusion: the reasons for vaccine hesitancy in the families of children found in this study threaten advancements in the struggle against vaccine-preventable diseases.  Contributions to the practice: government bodies, managers, and health unit nurses should be co-responsible for efficient measures to implement health education in this public, creating a bond of trust to reduce the risks from the increase in vaccine hesitancy and reduction in vaccine coverage in the country. 


Sales HMTB, Morais LM, Morais MKL, Batista NSD, Rodrigues RFB, Bomfim VB. Reducing vaccine coverage in Brazil: na integrative review. Braz J Health Rev. 2023;6(1):3752-63. doi:

Cardin VSG, Nery LMG. Hesitação vacinal: direito constitucional à autonomia individual ou um atentado à proteção coletiva? Prisma Jur. 2019;18(2):224-40. doi:

Sato APS, Boing AC, Almeida RLF, Xavier MO, Moreira RS, Martinez EZ, et al. Measles vaccination in Brazil: where have we been and where are we headed? Ciênc Saúde Coletiva. 2023;28(2):351-62. doi:

Moura PM, Costa GR, Pamplona YAP, Martins LC, Barbieri CLA. Série histórica da cobertura vacinal da BCG na região metropolitana da baixada santista de 2010 a 2018. Leopoldianum [Internet]. 2021 [cited May 29, 2023];47(132):23-34. Available from:

Bedford H, Attwell K, Danchin M, Marshall H, Corben P, Leask J. Vaccine hesitancy, refusal and access barriers: The need for clarity in terminology. Vaccine. 2018;36(44):6556-8. doi:

Goes FGB, Santos AST, Lucchese I, Silva LJ, Silva LF, Silva MA. Best practices in newborn care in covid-19 times: an integrative review. Texto Contexto Enferm. 2020;29e20200242. doi:

Bramer CA, Kimmins LM, Swanson R, Kuo J, Vranesich P, Jacques-Carroll LA, et al. Decline in child vaccination coverage during the COVID-19 pandemic - Michigan care improvement registry, May 2016-May 2020. MMWR Morb Mortal Wkly Rep. 2020;69(20):630-1. doi:

Santoli JM, Lindley MC, DeSilva MB, Kharbanda EO, Daley MF, Galloway L, et al. Effects of the COVID-19 pandemic on routine pediatric vaccine ordering and administration – United States. MMWR Morb Mortal Wkly Rep. 2020;69(19):591-3. doi:

Olson O, Berry C, Kumar N. Addressing parental vaccine hesitancy towards childhood vaccines in the United States: a systematic literature review of communication interventions and strategies. Vaccines (Basel). 2020;8(4):590. doi:

Domingues CMAS, Maranhão AGK, Teixeira AM, Fantinato FFS, Domingues RAS, et al. The Brazilian national immunization program: 46 years of achievements and challenges. Cad Saúde Pública. 2020;36(2):e00222919. doi:

United Nations Children’s Fund. The state of the world’s children 2023: for every child, vaccination, UNICEF innocent – global office of research and foresight, Florence, April [Internet]. 2023 [cited May 20, 2023]. Available from:

Gentile A, Pacchiotti AC, Giglio N, Nolte MF, Talamona N, Rogers V, et al. Vaccine hesitancy in Argentina Validation of WHO scale for parents. Vaccine. 2021;39(33):4611-9. doi:

Guimarães MGS, Branco FLCC, Guzmán HO, Braña AM, Estrada CHML, Arróspide N, et al. Avaliação da cobertura vacinal e fatores associados à aderência ao calendário vacinal em crianças menores de 5 anos em Iñapari, na Amazônia Peruana. Sci Naturalis [Internet]. 2020 [cited May 20, 2023];2(1):72-83. Available from:

Procianoy GS, Junior FR, Lied AF, Jung LFPP, Souza MCSC. Impacto da pandemia do COVID-19 na vacinação de crianças de ate um ano de idade: um estudo ecológico. Ciênc Saúde Coletiva. 2022;27(3):969-78. doi:

Terzi Ö, Gülen EM, Dündar C. The causes of parental vaccine refusal results of a survey from Giresun, Turkey. Turk J Pediatr. 2021;63(4):618-25. doi:

Dubé E, MacDonald NE. How can a global pandemic affect vaccine hesitancy? Expert Rev Vaccines. 2020;19(10):899-901. doi:

Toso BRGO, Vieira CS, Furtado MCC, Bonati PCR. Ações de enfermagem no cuidado à criança na atenção primária durante a pandemia de COVID-19. Rev Soc Bras Enferm Ped. 2020;20(Especial COVID-19):6-15. doi:

Mcdonald HI, Tessier E, White JN, Woodruff M, Knowles C, Bates C, et al. Early impact of the coronavirus disease (COVID-19) pandemic and physical distancing measures on routine childhood vaccinations in England, January to April 2020. Euro Surveill. 2020;25(19):2000848. doi:

Khawaja UA, Franchi T, Pedersini P, Tovani-Palone MR. Declining rates of global routine vaccination coverage amidst the COVID-19 syndemic: a serious public health concern. Einstein (São Paulo). 2021;19:eED6552. doi:

Iori DM, Siqueira VMC, Almeida CR, Labegalini CMG. Factors influencing vaccine access by mother’s users of the Primary Healt Care. Res Soc Dev. 2021;10(4):e28010414176. doi:

Sato APS. Pandemic and vaccine coverage: challenges of returning to schools. Rev Saúde Pública. 2020;54:115. doi:

Causey K, Fullman N, Sorensen RJD, Galles NC, Zheng P, Aravkin A, et al. Estimating global and regional disruptions to routine childhood vaccine coverage during the COVID-19 pandemic in 2020: a modelling study. Lancet. 2021;398(10299):522-34. doi:

Abbas K, Procter SR, Zandvoort K, Clark A, Funk S, Mengistu S, et al. Routine childhood immunisation during the COVID-19 pandemic in Africa: a benefit-risk analysis of health benefits versus excess risk of SARS-CoV-2 infection. Lancet Glob Health. 2020;8(10):E1264-E1272. doi:

Shibukawa BMC, Uema RTB, Piran CMG, Fonseca BS, Furtado MD, Merino MFGL, et al. Repercussões da pandemia de COVID-19: assistência da população pediátrica na Atenção Primária à Saúde. Rev Rene. 2022;23:e72798. doi:

Donalisio MR, Boing AC, Sato APS, Martinez EZ, Xavier MO, Almeida RLF, et al. Vaccination against poliomyelitis in Brazil from 2011 to 2021: successes, setbacks and challenges ahead. Ciênc Saúde Coletiva. 2023;28(2):337-50. doi:

Souza RR, Vieira MG, Lima Jr CJF. The integral child health care in the Federal District – Brazil. Ciênc Saúde Coletiva. 2019;24(6):2075-84. doi:



How to Cite

Viana, I. da S., Cursino, E. G., Silva, L. F. da, Machado, M. E. D., & Vaz, E. M. C. (2023). Vaccine hesitancy in families of children during the COVID-19 pandemic. Rev Rene, 24, e89253.



Research Article

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