Fatores associados à completude vacinal contra hepatite B entre profissionais de saúde da atenção primária

Cecília Natielly da Silva Gomes; Danielle Nedson Rodrigues de Mâcedo; Luany do Nascimento Feitosa; Emanoelle Fernandes Silva; Maria Laura de Lima Brito Magalhães; Breno Dias de Oliveira Martins; Rosilane de Lima Brito  Magalhães

doi:10.15253/2175-6783.20242593101

Authors

Cecília Natielly da Silva Gomes Universidade Federal do Piauí https://orcid.org/0000-0002-9681-2331
Danielle Nedson Rodrigues de Mâcedo Universidade Federal do Piauí https://orcid.org/0000-0002-8804-6323
Luany do Nascimento Feitosa Universidade Federal do Piauí https://orcid.org/0009-0007-5754-2731
Emanoelle Fernandes Silva Universidade Federal do Piauí https://orcid.org/0000-0002-4328-6155
Maria Laura de Lima Brito Magalhães Universidade Federal do Ceará https://orcid.org/0009-0003-6502-2876
Breno Dias de Oliveira Martins niversidade Federal do Piauí https://orcid.org/0009-0006-7835-7861
Rosilane de Lima Brito Magalhães niversidade Federal do Piauí https://orcid.org/0000-0001-9695-1350

DOI:

https://doi.org/10.15253/2175-6783.20242593101

Keywords:

Hepatitis B; Primary Health Care; Seroconversion; Hepatitis B Vaccines.

Abstract

Objective: to analyze factors associated with full hepatitis B vaccination in primary health care workers. Methods: cross-sectional research involving primary care health workers through the application of an instrument, verification of vaccination records, and blood collection to detect serological markers. Results: the prevalence of complete vaccination records was 108 (68.5%). White, brown, and Asian persons were significantly associated (p<0.05) with a reduction in the prevalence of full vaccination records; the same was true for having more than one employment. Having finished high school/technical education or having higher education/specializations were associated with complete records. Conclusion: full vaccination was satisfactory, showing a high prevalence. Social factors, such as ethnicity, educational level, and the number of employments influenced full vaccination. Contributions to practice: this study can guide practices and interventions in the field of health, in order to promote the health of primary care workers.

References

Nikolopoulou GB, Tzoutzas I, Tsakris A, Maltezou HC. Hepatitis B in healthcare personnel: an update on the global landscape. Viruses. 2023;15(12):2454. doi: https://doi.org/10.3390/v15122454

Oliveira VMC, Gomes CNS, Rocha DM, Abreu WJCP, Galvão MTG, Magalhães RLB. Nurses’ knowledge, attitudes and practices regarding hepatitis B: an integrative review. Texto Contexto Enferm. 2022;31:e20210187. doi: https://doi.org/10.1590/1980-265X-TCE-2021-0187

Mohanty P, Jena P, Patnaik L. Vaccination against hepatitis B: a scoping review. Asian Pac J Cancer Prev. 2020;21(12):3453-9. doi: https://doi.org/10.31557/APJCP.2020.21.12.3453

Alburqueque IC, Soeiro VMS, Lima RA, Ferreira ASP. Trends and spatial distribution of hepatitis B in pregnant women in Brazil. Rev Bras Saúde Mater Infant. 2024;24:e20230091. doi: https://doi.org/10.1590/1806-9304202400000091-en

Ministério da Saúde (BR). Manual dos Centros de Referência para Imunobiológicos Especiais [Internet]. 2023 [cited Feb 14, 2024]. Available from: https://www.gov.br/saude/pt-br/vacinacao/arquivos/manual-dos-centros-de-referencia-para-imunobiologicos-especiais_6a-edicao_2023.pdf

Obiri-Yeboah D, Awuku YA, Adjei G, Cudjoe O, Benjamin AH, Obboh E, et al. Post Hepatitis B vaccination sero-conversion among health care workers in the Cape Coast Metropolis of Ghana. PLoS One. 2019;14(6):e0219148. doi: https://doi.org/10.1371/journal.pone.0219148

Hussein NA, Ismail AM, Jama SS. Assessment of hepatitis B vaccination status and associated factors among healthcare workers in Bosaso, Puntland, Somalia 2020. Biomed Res Int. 2022;2022:9074294. doi: https://dx.doi.org/10.1155/2022/9074294

Garbin CAS, Vanzo KLT, Moimaz SAS, Garbin AJÍ, Chiba FY. Vaccination coverage and immunity against hepatitis B in public health dentists. Rev Soc Bras Med Trop. 2019;52:e20180534. doi: https://doi.org/10.1590/0037-8682-0534-2018

Quirino EMB, Dourado CARO, Andrade IKL, Lima MCL, Pinho CM, Silva MAS, et al. Exposure to biological materials: work accidents among health professionals in the state of Pernambuco. Rev Epidemiol Control Infect. 2020;10(4):1-12. doi: https://doi.org/10.17058/reci.v10i4.15296

Berhan Z, Malede A, Gizeyatu A, Sisay T, Lingerew M, Kloos H, et al. Prevalence and associated factors of needle stick and sharps injuries among healthcare workers in northwestern Ethiopia. PLoS One. 2021;16(9):e0252039. doi: https://doi.org/10.1371/journal.pone.0252039

Araújo TM, Souza FD, Pinho PD. Vacinação e fatores associados entre trabalhadores da saúde. Cad Saude Pública. 2019;35(4):e00169618. doi: https://doi.org/10.1590/0102-311x00169618

Ansa GA, Ofori KNA, Houphouet EE, Amoabeng AA, Sifa JS, Amenuveve CK, et al. Hepatitis B vaccine uptake among healthcare workers in a referral hospital, Accra. Pan Afr Med J. 2019;33:96. doi: https://doi.org/10.11604/pamj.2019.33.96.18042

Kisangau EN, Awour A, Juma B, Odhiambo D, Muasya T, Kiio SN, et al. Prevalence of hepatitis B virus infection and uptake of hepatitis B vaccine among healthcare workers, Makueni County, Kenya 2017. J Public Health (Oxf). 2019;41(4):765-71. doi: https://doi.org/10.1093/pubmed/fdy186

Ndunguru B, Wilfred D, Kapesa A, Kilonzo SD, Mirambo M, Hyera F, et al. Low uptake of hepatitis B vaccination among healthcare workers in primary health facilities in Mwanza region, North-Western Tanzania. Front Public Health. 2023;11:1152193. doi: https://doi.org/10.3389/fpubh.2023.1152193

Farias Junior YC, Souza FO, Heliotério MC, Araújo TM, Pinho PS. Hepatitis B vaccination and serology among health personnel in a municipality in the Recôncavo Baiano, Brazil, 2019. Rev Bras Med Trab. 2023;21(4):e2022975. https://doi.org/10.47626/1679-4435-2022-975

Pujol FH, Toyé RM, Loureiro CL, Jaspe RC, Chemin I. Hepatitis B eradication: vaccine as a key player. Am J Transl Res [Internet]. 2023 [cited Feb 14, 2024];15(8):4971-83. Available from:https://e-century.us/web/journal_toc.php?journal=ajtr&volume=15&number=8

Alshammari TM, Aljofan M, Subaie G, Hussain T. Knowledge, awareness, attitude, and practice of health-care professionals toward hepatitis B disease and vaccination in Saudi Arabia. Hum Vaccin Immunother. 2019;15(12):2816-23. doi: https://doi.org/10.1080/21645515.2019.1629255

Ngum AM, Laure SJ, Tchetnya X, Tambe TA, Ngwayu CN, Wirsiy FS, et al. Vaccination against Hepatitis B among health care workers in the Bamenda Health District: influence of knowledge and attitudes, Cameroon. Pan Afr Med J. 2021;40:216. doi: https://doi.org/10.11604/pamj.2021.40.216.16856

Hiva S, Negar K, Mohammad-Reza P, Gholam-Reza G, Mohsen A, Ali-Asghar NG, et al. High level of vaccination and protection against hepatitis B with low rate of HCV infection markers among hospital health care personnel in north of Iran: a cross-sectional study. BMC Public Health. 2020;20(1):920. doi: https://dx.doi.org/10.1186/s12889-020-09032-6

Momplaisir FM, Kuter BJ, Ghadimi F, Browne S, Nkwihoreze H, Feemster KA, et al. Racial/ethnic differences in COVID-19 vaccine hesitancy among health care workers in 2 large academic hospitals. JAMA Netw Open. 2021;4(8):e2121931. doi: http://doi.org/10.1001/jamanetworkopen.2021.21931

Souza ARSV, Melo RL, Araújo BRO. Raça, gênero e classe uma revisão integrativa sobre os impactos dos determinantes sociais da saúde na infecção por COVID-19. Cad Grad Ciênc Biol Saúde [Internet]. 2022 [cited Apr 26, 2024];7(2):99-99. Available from: https://periodicos.set.edu.br/fitsbiosaude/article/view/9934

Leão DV, Belém RJ, Almeida KV, Reis VLR, Reis HS, Santos FS. Perfil epidemiológico das hepatites infectocontagiosas no estado do Pará. Rev Eletr Acervo Saúde. 2021;13(4):e6790-e6790. doi: https://doi.org/10.25248/reas.e6790.2021

Carpenter C, Bernardo B, Adeyanju T, Washington C, Fisher JL, Young G, et al. The association between internet use to obtain health information and receiving three doses of the Hepatitis B vaccine in a multi-ethnic population in Ohio. Prev Med Rep. 2023;33:102203. doi: https://doi.org/10.1016/j.pmedr.2023.102203

Oliveira VMC, Galvão MTG, Nunes RV, Carvalho MSM, Gomes CNS, Magalhães RLB. Hepatitis B vaccine adherence among homeless people. Rev Rene. 2021;22:e60690. doi: https://doi.org/10.15253/2175-6783.20212260690

Senoo-Dogbey VE, Anto F, Quansah R, Danso-Appiah A. Completion of three-dose hepatitis B vaccination cycle and associated factors among health care workers in the greater Accra region of Ghana. PLoS One. 2024;19(4):e0298771. doi: https://doi.org/10.1371/journal.pone.0298771

Awoke N, Mulgeta H, Lolaso T, Tekalign T, Samuel S, Obsa MS, et al. Full-dose hepatitis B virus vaccination coverage and associated factors among health care workers in Ethiopia: a systematic review and meta-analysis. PLoS One. 2020;15(10):e0241226. doi: https://doi.org/10.1371/journal.pone.024122

Duodu PA, Darkwah E, Agbadi P, Duah HO, Nutor JJ. Prevalence and geo-clinicodemographic factors associated with hepatitis B vaccination among healthcare workers in five developing countries. BMC Infect Dis. 2022;22(1):599. doi: https://doi.org/10.1186/s12879-022-07556-3

Oni OI, Osho OP, Oluwole MT, Osho ES, Ogungbeje A, Raji HM. Assessing the level of knowledge, uptake of hepatitis B virus vaccine, and its determinants among health workers across various levels of health facilities in Ondo, South West, Nigeria. Egypt J Intern Med. 2022;34:80. doi: https://doi.org/10.1186/s43162-022-00167-z