Influência da variação da creatinina sérica no desfecho do paciente com lesão renal aguda

Autores/as

DOI:

https://doi.org/10.15253/2175-6783.20181933348

Palabras clave:

Lesão Renal Aguda; Creatinina; Mortalidade.

Resumen

Objetivo: identificar a influência de variações na creatinina sérica sobre o desfecho dos pacientes com lesão renal aguda. Métodos: estudo observacional prospectivo. A amostra foi composta de 85 pacientes que evoluíram com comprometimento renal. Os dados foram extraídos do prontuário e registrados em questionário construído previamente. Valores com p≤0,05 foram considerados significativos. Resultados: a maioria dos pacientes era do sexo masculino (51,8%) e idosos (66±14 anos). A redução da função renal ocorreu em graduações diferentes, haja vista que 35,3% evoluiu com risco para lesão renal (estágio 1) e um menor percentual (14,1%) foi acometido mais gravemente (estágios 2 e 3), respectivamente. O clearance de creatinina aumentou progressivamente revelando recuperação da função renal ao longo do acompanhamento. Pacientes com lesão ou falência renal (estágios 2 ou 3) evoluíram mais frequentemente ao óbito (p=0,027). Conclusão: variações na creatinina sérica podem agravar o desfecho do paciente ao longo do período de internação.

Citas

Petronijevic Z, Selim G, Petkovska L, Georgievska-Ismail L, Spasovski G, Tozija L. The effect of treatment on short-term outcomes in elderly patients with acute kidney injury. Open Access Maced J Med Sci. 2017; 5(5):635-40. doi: http://dx.doi.org/10.3889/oamjms.2017.148

Rewa O, Basgshaw SM. Acute kidney injury-epidemiology, outcomes and economics. Nat Rev Nephrol. 2014; 10(4):193-207. doi: http://dx.doi.org/10.1038/nrneph.2013.282

Kidney Disease Improving Global Outcomes (KDIGO). Working Group. Definition and classification of acute kidney injury. Kidney Int Suppl [Internet]. 2012 [cited July 02, 2018]; 2:19-36. Available from: http://www.kdigo.org/clinical_practice_guidelines/pdf/KDIGO%20AKI%20Guideline.pdf

Soares LO, Brune MFSS. A avaliação da função renal em adultos por meio da taxa de filtração glomerular e microalbuminúrica. Rev Bras Pesq Saúde. 2017; 19(3):62-8. doi: https://doi.org/10.21722/rbps.v19i3.19566

Koeze J, Keus F, Dieperink W, van der Horst IC, Zijlstra JG, Van Meurs M. Incidence, timing and outcome of AKI in critically ill patients varies with the definition used and the addition of urine output criteria. BMC Nephrol. 2017; 18(1):70. doi: http://dx.doi.org/10.1186/s12882-017-0487-8

Talib S, Sharif F, Manzoor S, Yaqub S, Kashif W. Charlson comorbidity index for prediction of outcome of acute kidney injury in critically ill patients. Iran J Kidney Dis [Internet]. 2017 [cited July 04, 2018];11(2):115-23. Available from: http://www.ijkd.org/index.php/ijkd/article/view/2855/907

Siew ED, Davenport A. The growth of acute kidney injury: a rising tide or just closer attention to detail? Kidney Int. 2015; 87(1): 46-61. doi: http://dx.doi.org/10.1038/ki.2014.293

Lysak N, Bihorac A, Hobson C. Mortali-ty and cost of acute and chronic kidney di-seaseaftercardiac surgery. Curr Opin Anaesthsi-ol. 2017; 30(1):113-7. doi: http://dx.doi.org/10.1097/ACO.0000000000000422

Pickering JW, Endre ZH. Back-calculating baseline creatinine with MDRD misclassifies acute kidney Injury in the Intensive Care Unit. Clin J Am Soc Nephrol. 2010; 5(7):1165-73. doi: http://dx.doi.org/10.2215/CJN.08531109

Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbi- dity in longitudinal studies: development and va- lidation. J Chronic Dis [Internet]. 1987 [cited July 06, 2018]; 40(5):373-83. Available from: http://www.aqc.ch/download/HSM_Suppl_8_charlson.pdf

Schiffl H. Prevention of severe acute kidney injury by implementation of care bundles: Some progress but still a lot of work ahead. Saudi J Kidney Dis Transpl. 2018; 29(3):513-7. doi: http://dx.doi.org/10.4103/1319-2442.235195

Hoste EA, Bagshaw SM, Bellomo R, Cely CM, Col-man R, Cruz DN, et al. Epidemiology of acute kid-ney injury in critically ill patients: the multina-tional AKI-EPI study. Intensive Care Med. 2015; 41(8):1411-23. doi: http://dx.doi.org/10.1007/s00134-015-3934-7

Hamzić-Mehmedbašić A, Rašić S, Balavac M, Rebić D, Delić-Šarac M, Durak-Nalbantić A. Prognostic indicators of adverse renal outcome and death in acute kidney injury hospital survivors. J Renal InjPrev [Internet].2016 [cited 2018 July 10]; 5(2):61-8. doi: http://dx.doi.org/10.15171/jrip.2016.14

Petronijevic Z, Selim G, Petkovska L, Georgievska-Ismail L, Spasovski G, Tozija L. The Effect of Treatment on Short-Term Outcomes in Elderly Patients with Acute Kidney Injury. Open Access Maced J Med Sci. 2017; 5(5):635-40. doi: http://dx.doi.org/10.3889/oamjms.2017.148

Brown JR, Rezaee ME, Marshall EJ, Matheny ME. Hospital mortality in the United States following acute kidney injury. Biomed Res Int. 2016; 2016:4278579. doi: http://dx.doi.org/10.1155/2016/4278579

Garasto S, Fusco S, Corica F, Rosignuolo, Marino A, Montesanto, et al. Estimating glomerular filtration rate in older people. Biomed Res Int. 2014; 2014:916542. doi: http://dx.doi.org/10.1155/2014/916542

Rigonatto MCL, Magro MCS. Risk for acute kidney injury in primary health care. Rev Bras Enferm. 2018; 71(1):20-5. doi: http://dx.doi.org/10.1590/0034-7167-2016-0551

Moura SLF, Duarte TTP, Magro MCS. Severity and outcome of patientes with acute. Rev Enferm UFPE on line [Internet]. 2017 [cited July 13, 2018]; 11(11):4319-25. Available from: https://periodicos.ufpe.br/revistas/revistaenfermagem/article/viewFile/23537/24677

Domingueti CP, Fóscolo RB, Dusse LMS, Reis JS, Carvalho MDG, Gomes KB, et al. Association of different biomarkers of renal function with D-di-mer levels in patients with type 1 diabetes melli-tus (renal biomarkers and D-dimer in diabetes). Arch Endocrinol Metab. 2018; 62(1):27-33. doi: http://dx.doi.org/10.20945/2359-3997000000003

Muthuppalaniappan VM, Yaqoob MM. Ethnic/race diversity and diabetic kidney disease. J Clin Med. 2015; 4(8):1561-5. doi: http://dx.doi.org/10.3390/jcm4081561

Publicado

2018-12-26

Cómo citar

Silva, H. M. da, Duarte, T. T. da P., & Magro, M. C. da S. (2018). Influência da variação da creatinina sérica no desfecho do paciente com lesão renal aguda. Rev Rene, 19, e33348. https://doi.org/10.15253/2175-6783.20181933348

Número

Sección

Research Article

Artículos más leídos del mismo autor/a