Nível de adesão e fatores associados ao uso de medicamentos em pacientes com diabetes mellitus

Autores

DOI:

https://doi.org/10.15253/2175-6783.20242594393

Palavras-chave:

Adesão à Medicação; Diabetes Mellitus; Tratamento Farmacológico; Cooperação e Adesão ao Tratamento.

Resumo

Objetivo: identificar o nível de práticas de adesão medicamentosa e os fatores associados entre pacientes com diabetes mellitus. Métodos: estudo descritivo transversal, realizado entre pacientes com diabetes mellitus em centros de saúde na Arábia Saudita. Foram selecionados 218 participantes com base nos critérios de inclusão e exclusão. A Escala de Prática de Adesão Medicamentosa, com pontuação máxima de 50, foi utilizada para coletar os dados. Resultados: a média da pontuação de prática de adesão medicamentosa foi de 28,64 ± 8,47. 65,1% dos participantes apresentaram adesão moderada, 27,5% alta e 7,3% baixa. A análise de regressão múltipla mostrou que o nível educacional (p=0,000), comorbidade (p=0,001), monitoramento da glicemia (p=0,002), complicações (p=0,000), terapias alternativas (p=0,000) e nível de HbA1C (p=0,000) foram preditores significativos. Conclusão: identificou-se práticas de adesão moderada aos medicamentos. Esta, também, foi significativamente associada à renda, idade, estado civil, tamanho da família, nível educacional, ocupação, anos de uso de medicamentos para diabetes, comorbidade, uso de medicamentos para outros problemas, número de medicamentos antidiabéticos, fonte de adesão aos medicamentos, monitoramento regular, complicações e nível de HbA1C. Contribuições para a prática: estudar os preditores das práticas de adesão medicamentosa do Diabetes Mellitus contribuirá para a melhoria das intervenções de saúde.

Referências

International Diabetes Federation. IDF Diabetes Atlas. Middle East and North Africa (MENA) Diabetes Report 2000-2045 [Internet]. 2021 [cited Oct 24, 2024]. Available from: https://diabetesatlas.org/data/en/region/4/mena.html

Pertiwi MV, Alfian R, Nita Y, Athiyah U. IAI special edition: medication adherence of diabetes mellitus patients in Indonesia: a systematic review. Pharm Educ. 2022;22(2):188-93. doi: https://doi.org/10.46542/pe.2022.222.188193

Waari G, Mutai J, Gikunju J. Medication adherence and factors associated with poor adherence among type 2 diabetes mellitus patients on follow-up at Kenyatta National Hospital, Kenya. Pan Afr Med J. 2018;29:82. doi: https://dx.doi.org/10.11604/pamj.2018.29.82.12639

AlQarni K, AlQarni EA, Naqvi AA, AlShayban DM, Ghori SA, Haseeb A, et al. Assessment of medication adherence in saudi patients with type II diabetes mellitus in Khobar city, Saudi Arabia. Front Pharm. 2019;10:1306. doi: https://dx.doi.org/10.3389/fphar.2019.01306

Asheq A, Ashames A, Al-Tabakha M, Hassan N, Jairoun A. Medication adherence in type 2 diabetes mellitus patients during Covid-19 pandemic: a cross-sectional study from the United Arab Emirates. F1000Res. 2021;10:435. doi: https://dx.doi.org/10.12688/f1000research.51729.2

Khunti N, Khunti N, Khunti K. Adherence to type 2 diabetes management. Br J Diabetes. 2019;19(2):99-104. doi: https://doi.org/dx.10.15277/bjd.2019.223

Alnaim MM, Alrasheed A, Alkhateeb AA, Aljaafari MM, Alismail A. Prevalence of microvascular complications among patients with type 2 diabetes mellitus who visited diabetes clinics in Saudi Arabia. Saudi Med J. 2023;44(2):211-7. doi: https://doi.org/10.15537/smj.2023.44.2.20220719

Zaki SM, El Karsh DS, Faden TM, Almghamsi LT, Fathaldin JO, Alhazmi OA. Diabetic foot complications in Saudi Arabia: a retrospective study. Cureus. 2024;16(2):e53531. doi: https://dx.doi.org/10.7759/cureus.53531

Kao C-C, Hsieh H-M, Lee DY, Hsieh K-P, Sheu S-J. Importance of medication adherence in treatment needed diabetic retinopathy. Sci Rep. 2021;11:19100. doi: https://dx.doi.org/10.1038/s41598-021-98488-6

Doya IF, Yahaya JJ, Ngaiza AI, Bintabara D. Low medication adherence and its associated factors among patients with type 2 diabetes mellitus attending Amana Hospital in Dar es Salaam, Tanzania: a cross-sectional study. Int Health. 2024;16(2):200-7. doi: https://doi.org/10.1093/inthealth/ihad042

Alomar MJ, Al-Ansari KR, Hassan NA. Comparison of awareness of diabetes mellitus type II with treatment’s outcome in term of direct cost in a hospital in Saudi Arabia. World J Diabetes. 2019;10(8):463-72. doi: https://doi.org/10.4239/wjd.v10.i8.463

Kingdom of Saudi Arabia. Saudi vision 2030. Vision 2030 Projects [Internet]. 2024 [cited Oct 24, 2024]. Available from: https://www.vision2030.gov.sa/en

Kim J, Combs K, Down J, Tillman F. Medication adherence: the elephant in the room. US Pharm [Internet]. 2018 [cited Oct 24, 2024];43(1)30-4. Available from: https://www.uspharmacist.com/article/medication-adherence-the-elephant-in-the-room

Alsanosi S, Hariri N, Alshanberi A, Alanazi I, Al-Eissa M, Alhindi Y. Adherence to chronic medications among type 2 diabetic patients in primary heath care centres: a cross-sectional study. Med Sci. 2022;26:ms387e2458. doi: https://doi.org/10.54905/disssi/v26i127/ms387e2458

Alsaidan AA, Alotaibi SF, Thirunavukkarasu A, ALruwaili BF, Alharbi RH, Arnous MM, et al. Medication adherence and its associated factors among patients with type 2 diabetes mellitus attending primary health centers of eastern province, Saudi Arabia. Medicina (Kaunas). 2023;59(5):989. doi: https://doi.org/10.3390/medicina59050989

Murwanashyaka JD, Ndagijimana A, Biracyaza E, Sunday FX, Umugwaneza M. Non-adherence to medication and associated factors among type 2 diabetes patients at Clinique Medicale Fraternite, Rwanda: a cross-sectional study. BMC Endocr Disord. 2022;22(1):219. doi: https://doi.org/10.1186/s12902-022-01133-0

Othman G, Ali F, Ibrahim MIM, Al-Worafi YM, Ansari M, Halboup AM. Assessment of anti-diabetic medications adherence among diabetic patients in Sana’a City, Yemen: a cross sectional study. J Pharm Res Int. 2020;32(21):114-22. doi: https://doi.org/10.9734/jpri/2020/v32i2130761

Islam SMS, Islam MDT, Uddin R, Tansi T, Talukderet S, Sarker F, et al. Factors associated with low medication adherence in patientswith Type 2 diabetes mellitus attending a tertiary hospital in Bangladesh. Lifestyle Med. 2021;2(4):e47. doi: https://doi.org/10.1002/lim2.47

Fallatah MS, Alghamdi GS, Alzahrani AA, Sadagah MM, Alkharji TM. Insights into medication adherence among patients with chronic diseases in Jeddah, Saudi Arabia: a cross-sectional study. Cureus. 2023;15(4):e37592. doi: https://dx.doi.org/10.7759/cureus.37592

Gu L, Wu S, Zhao S, Zhou H, Zhang S, Gao M, et al. Association of social support and medication adherence in Chinese patients with type 2 diabetes mellitus. J Pediatr Psychol. 2017;14(12):1522. doi: https://doi.org/10.3390/ijerph14121522

Wulandari N, Maifitrianti M, Hasanah F, Atika S, Dini PR. Medication adherence assessment among patients with type 2 diabetes mellitus treated polytherapy in Indonesian community health center: A cross sectional-study. J Pharm Bioallied Sci. 2020;12(Suppl 2):758-62. doi: https://dx.doi.org/10.4103/jpbs.JPBS_257_19

Rusminingsih E, Purnomo RT. Relationship of patient characteristics with medication adherence in type 2 DM. Indones J Global Health Res. 2022;4(3):603-10. doi: http://doi.org/10.37287/ijghr.v4i3.1316

Dinkova R, Marinov L, Doneva M, Kamusheva M. Medication adherence among patients with diabetes mellitus and its related factors—a real-world pilot study in Bulgaria. Medicina. 2023;59(7):1205. doi: https://doi.org/10.3390/medicina59071205

Alodhaib G, Alhusaynan I, Mirza A, Almogbel Y. Qualitative exploration of barriers to medication adherence among patients with uncontrolled diabetes in Saudi Arabia. Pharmacy (Basel). 2021;9(1):16. doi: http://doi.org/10.3390/pharmacy9010016

Rashidi A, Whitehead L, Kaistha P. Nurses’ perceptions of factors influencing treatment engagement among patients with cardiovascular diseases: a systematic review. BMC Nurs. 2021;20(1):251. doi: http://doi.org/10.1186/s12912-021-00765-2

Presley B, Groot W, Pavlova M. Pharmacy-led interventions to improve medication adherence among adults with diabetes: a systematic review and meta-analysis. Res Social Adm Pharm. 2019;15(9):1057-67. doi: https://dx.doi.org/10.1016/j.sapharm.2018.09.021

Alhammadi NA, Al Qahtani AA, Hosiky MF, Al Shahrani FS, Al Shehri SM, Al Ghamdi MA, et al. Public awareness of diabetes complications and its effect on treatment compliance in Asir region, Saudi Arabia. J Family Med Primary Care. 2022;11(11):6812-7. doi: https://dx.doi.org/10.4103/jfmpc.jfmpc_422_22

Publicado

2024-11-20

Como Citar

Thangam, M. M. N. (2024). Nível de adesão e fatores associados ao uso de medicamentos em pacientes com diabetes mellitus . Rev Rene, 25, e94393. https://doi.org/10.15253/2175-6783.20242594393

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