Survival rate after paraquat poisoning: impact of emergency clinical and laboratory variables

Laurindo Pereira de Souza; Rafael Ayres Romanholo; Cidia  Vasconcellos

doi:10.15253/2175-6783.20212270836

Autores

Laurindo Pereira de Souza Instituto de Assistência Médica ao Servidor Público Estadual de São Paulo https://orcid.org/0000-0002-9890-2621
Rafael Ayres Romanholo Instituto Federal de Rondônia https://orcid.org/0000-0002-3210-3448
Cidia Vasconcellos Universidade de São Paulo https://orcid.org/0000-0003-3055-1084

DOI:

https://doi.org/10.15253/2175-6783.20212270836

Palavras-chave:

Envenenamento; Paraquat; Emergências; Taxa de Sobrevida; Ecossistema Amazônico.

Resumo

Objetivo: analisar a associação da sobrevida às medidas de atendimento de emergência, sintomas clínicos e marcadores bioquímicos usados para pacientes intoxicados por paraquat. Métodos: coorte retrospectiva, norteada pela ferramenta Strengthening the Reporting of Observational Studies in Epidemiology. O protocolo de coleta e análise de dados foi baseado em duas fases: primeira, com o levantamento das fichas de investigação de intoxicações exógenas da Secretaria de Vigilância Epidemiológica; segunda, com a análise das informações nos prontuários médicos impressos. Resultados: dos 36(100%) pacientes investigados, 19(53,0%) sobreviveram; no tocante às manifestações clínicas, houve significância estatística para o sistema respiratório (p=0,003); no que tange às variáveis bioquímicas, houve significância estatística para as enzimas hepáticas. As medidas de emergências inicias 13(56,5%) dos sobreviventes receberam lavagem gástrica com carvão ativado. Conclusão: observou-se falta de eficácia dos impactos das medidas de atendimento de emergência e dos medicamentos em aumentar a sobrevida dos pacientes.

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